A pharmacokinetic basis for the efficacy of 4-amino-6-trichloroethenyl-1,3,-benzenedisulfonamide against Fasciola hepatica in the rat

J Parasitol. 1979 Aug;65(4):555-61.
No abstract available

MeSH terms

  • Animals
  • Antiplatyhelmintic Agents / blood
  • Antiplatyhelmintic Agents / metabolism
  • Antiplatyhelmintic Agents / pharmacology*
  • Carbonic Anhydrase Inhibitors
  • Chemical Phenomena
  • Chemistry
  • Erythrocytes / enzymology
  • Fasciola hepatica / drug effects*
  • Fasciola hepatica / metabolism
  • Fascioliasis / drug therapy*
  • Fascioliasis / metabolism
  • Liver / metabolism
  • Male
  • Rats
  • Sulfonamides / blood
  • Sulfonamides / metabolism
  • Sulfonamides / pharmacology*
  • Testis / metabolism
  • Trichloroethylene / analogs & derivatives
  • Trichloroethylene / pharmacology

Substances

  • Antiplatyhelmintic Agents
  • Carbonic Anhydrase Inhibitors
  • Sulfonamides
  • Trichloroethylene