Studies on the biosynthetic conversion of cholesterol into pregnenolone. Side chain cleavage of a t-butyl analog of 20 -hydroxycholesterol, (20R(-t-butyl-5-pregnene-3 ,20-diol, a compound completely substituted at C-22

MeSH terms

• Adrenal Glands / cytology
• Adrenal Glands / metabolism*
• Alcohols / chemical synthesis
• Alcohols / metabolism*
• Alkylation
• Animals
• Cattle
• Chemical Phenomena
• Chemistry
• Chromatography
• Chromatography, Thin Layer
• Female
• Lithium
• Mitochondria / metabolism
• Models, Chemical
• Organometallic Compounds
• Pregnanediol / urine
• Pregnanes / chemical synthesis
• Pregnanes / metabolism*
• Pregnenolone / biosynthesis*
• Rabbits
• Tritium