Investigations on sterols. 38. Synthesis of 1,2 -methylene-17 -acetoxy-9 ,10 -pregnanes, a class of potent progestational agents

J Med Chem. 1972 Dec;15(12):1288-92. doi: 10.1021/jm00282a022.
No abstract available

MeSH terms

  • Administration, Oral
  • Animals
  • Bridged-Ring Compounds / administration & dosage
  • Bridged-Ring Compounds / chemical synthesis
  • Bridged-Ring Compounds / pharmacology
  • Dose-Response Relationship, Drug
  • Female
  • Magnetic Resonance Spectroscopy
  • Pregnanes / administration & dosage
  • Pregnanes / chemical synthesis*
  • Pregnanes / pharmacology
  • Progestins / administration & dosage
  • Progestins / chemical synthesis*
  • Progestins / pharmacology
  • Rabbits
  • Spectrophotometry, Infrared
  • Structure-Activity Relationship
  • Uterus / drug effects

Substances

  • Bridged-Ring Compounds
  • Pregnanes
  • Progestins