Metabolism of the antihypertensive agent 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylic acid diethyl ester

J Pharm Sci. 1973 Apr;62(4):580-4. doi: 10.1002/jps.2600620407.
No abstract available

MeSH terms

  • Animals
  • Antihypertensive Agents / blood
  • Antihypertensive Agents / metabolism*
  • Antihypertensive Agents / urine
  • Biotransformation
  • Carbon Isotopes
  • Chromatography, Gas
  • Chromatography, Thin Layer
  • Dicarboxylic Acids / metabolism*
  • Dogs
  • Enzyme Induction
  • Esters / biosynthesis
  • Esters / blood
  • Esters / urine
  • Half-Life
  • Haplorhini
  • Microsomes, Liver / enzymology
  • Protein Binding
  • Pyridines / blood
  • Pyridines / metabolism*
  • Pyridines / urine
  • Rats

Substances

  • Antihypertensive Agents
  • Carbon Isotopes
  • Dicarboxylic Acids
  • Esters
  • Pyridines