Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue"

MeSH terms

• Adult
• Aged
• Anemia / chemically induced
• Carcinoma, Squamous Cell / drug therapy*
• Cell Division / drug effects
• Drug Eruptions
• Drug Synergism
• Facial Neoplasms / drug therapy*
• Female
• Head and Neck Neoplasms / drug therapy*
• Humans
• Laryngeal Neoplasms / drug therapy
• Leucovorin / administration & dosage
• Leucovorin / therapeutic use*
• Leukopenia / chemically induced
• Lip Neoplasms / drug therapy
• Male
• Methotrexate / administration & dosage
• Methotrexate / adverse effects
• Methotrexate / therapeutic use*
• Middle Aged
• Mouth Neoplasms / drug therapy*
• Mucous Membrane / drug effects
• Palatal Neoplasms / drug therapy
• Pharyngeal Neoplasms / drug therapy
• Tongue Neoplasms / drug therapy