Antigenic characteristics of normal and malignant human hematopoietic cells. Potential use of antigenic differences in cell separation and marrow transplantation

M J Cline; J H Fitchen; K Foon; R Billing

Antigenic characteristics of normal and malignant human hematopoietic cells. Potential use of antigenic differences in cell separation and marrow transplantation

Exp Hematol. 1979:7 Suppl 5:246-51.

Authors

M J Cline, J H Fitchen, K Foon, R Billing

PMID: 400688

Abstract

Recent studies using cytotoxic and cell separation techniques have identified differentiation-related antigens on human hematopoietic cells. These results, combined with bone marrow transplantation studies, have yielded a picture of antigenic modulation from the pluripotent hematopoietic stem cell through the differentiated end cells.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Antigens, Surface / analysis
Bone Marrow Transplantation
Cell Separation / methods
HLA Antigens / analysis
Hematopoietic Stem Cells / immunology*
Histocompatibility Antigens Class II / analysis
Humans
Leukemia, Lymphoid / immunology
Leukemia, Lymphoid / pathology

Substances

Antigens, Surface
HLA Antigens
Histocompatibility Antigens Class II