To comprehensively evaluate the structure and function of the bladder wall in children using multi-modal ultrasound (MMU). A total of 110 children without urinary symptoms admitted to the First Affiliated Hospital of Zhengzhou University from January 2022 to June 2023 were included prospectively. MMU was performed and the vesical volume (VV), bladder wall thickness (BWT), shear wave velocity (SWV) of the anterior wall, resistance index (RI) and vascularization index (VI) were measured in the filled and emptied bladder respectively, and the ultrasound bladder compliance (UBC) was also calculated. The differences in MMU parameters in children among different bladder states, age groups and sexes and the correlation between age and different MMU parameters were analyzed. The age of 110 children was (6.4±3.5) years, of which 60 were boys (54.5%). The VV [127.00 (79.00, 219.50) vs 6.65 (5.10, 9.60) ml, P<0.001] and SWV [(2.25±0.36) vs (1.54±0.20) m/s, P<0.001] of filling condition were higher than that of emptying condition, while BWT [(2.52±0.25) vs (6.72±0.74) mm, P<0.001] and VI [(4.36±0.52)% vs (8.15±1.75) %, P<0.001] were lower than that of emptying condition. There were no significant differences in VV, BWT, SWV, RI, VI and UBC between boys and girls under either bladder emptying or filling conditions (all P>0.05). BWT in emptying condition, VV and BWT in filling condition all increased with age (r was 0.706, 0.891 and 0.298, respectively, and all P<0.05). MMU in children contributes to the comprehensive evaluation of bladder wall, and the influence of age and bladder filling state should be considered when evaluating MMU parameters.
探讨多模态超声（MMU）对儿童膀胱壁结构与功能综合评估的价值。前瞻性收集2022年1月至2023年6月郑州大学第一附属医院因非泌尿系统症状就诊的110名儿童并行MMU检查，分别在膀胱充盈状态及排空状态下，测定膀胱容量（VV）、膀胱壁厚度（BWT）、前壁剪切波速度（SWV）、阻力指数（RI）和血管形成指数（VI），并计算超声膀胱顺应性（UBC）。分析膀胱不同充盈状态、年龄段、性别间MMU参数间的差异，年龄与不同MMU参数间的相关性。110名儿童年龄（6.4±3.5）岁，男童60名（54.5%）。膀胱充盈状态VV［127.00（79.00，219.50）比6.65（5.10，9.60）ml］及SWV［（2.25±0.36）比（1.54±0.20）m/s］高于排空状态（均P<0.001），BWT［（2.52±0.25）比（6.72±0.74）mm］及VI［（4.36±0.52）%比（8.15±1.75）%］低于排空状态（均P<0.001）。相同膀胱状态下，男童与女童间VV、BWT、SWV、RI、VI及UBC差异均无统计学意义（均P>0.05）。排空状态下BWT、充盈状态下VV及BWT与年龄呈正相关（r分别为0.706、0.891、0.298，均P<0.05）。MMU有助于综合评估儿童膀胱壁结构和功能，评估MMU参数时要考虑年龄及膀胱充盈状态的影响。.