A five-plex Hepatic Oncochip reveals EMT triplet correlated with BAP31 in liver cancer

Youjia Kong; Tengfei Zhuang; Xvshen Ding; Sirui Cai; Weijie Ding; Xiaoxiao Zhang; Yubo Sun; Bingquan Zhou; Yuanjie Sun; Shuya Yang; Xiyang Zhang; Kun Yang; Dongbo Jiang

doi:10.3389/fcell.2024.1478444

A five-plex Hepatic Oncochip reveals EMT triplet correlated with BAP31 in liver cancer

Front Cell Dev Biol. 2025 Jan 6:12:1478444. doi: 10.3389/fcell.2024.1478444. eCollection 2024.

Authors

Youjia Kong^#^{1

2}, Tengfei Zhuang^#¹, Xvshen Ding^#^{1

3}, Sirui Cai¹, Weijie Ding¹, Xiaoxiao Zhang⁴, Yubo Sun¹, Bingquan Zhou¹, Yuanjie Sun¹, Shuya Yang¹, Xiyang Zhang^{1

5}, Kun Yang^{1

2}, Dongbo Jiang^{1

2}

Affiliations

¹ Department of Immunology, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, Shaanxi, China.
² The Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, Shaanxi, China.
³ Department of Neurosurgery, Tangdu Hospital, Air-Force Medical University (The Fourth Military Medical University), Xi'an, Shaanxi, China.
⁴ Department of Information, Medical Supplies Center of PLA General Hospital, Beijing, China.
⁵ Military Medical Innovation Center, Air-Force Medical University (Fourth Military Medical University), Xi'an, Shaanxi, China.

^# Contributed equally.

No abstract available

Keywords: biomarkers; epithelialmesenchymal transition; fluorescence spectroscopy; liver cancer; multiplex immunohistochemistry.

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This study was supported by Program of the National Natural Science Foundation of China (No. 82203510 to DJ, No. 82073154 to KY), Medical Key Project of Xi’an (No. 24YSYJ0005 to DJ), the Key Research and Development Program of Shaanxi Province (2023-YBSF-198 to DJ), and Youth Promotion Project of Xi’an (No. 959202313100 to DJ).