Superiority of 18F-FAPI-42 PET/CT in Eosinophilic Gastrointestinal Disorders

Clin Nucl Med. 2024 Dec 30. doi: 10.1097/RLU.0000000000005658. Online ahead of print.

Abstract

We report a rare case of eosinophilic gastrointestinal disorders in a 60-year-old woman, which extensively involved the digestive tract from the esophagus, gastric, duodenum to the small intestine, depicted well by 18F-FAPI-42 PET/CT, superior to 18F-FDG PET/CT. Under the guidance of 18F-FAPI-42 PET/CT, the biopsy was successfully performed, and the diagnosis was established. This case highlights that 18F-FAPI-42 PET/CT may serve as a novel noninvasive method for evaluating eosinophilic gastrointestinal disorders.