Long-Term Visual Field Progression in X-Linked Retinitis Pigmentosa Patients

Alvilda Hemmingsen Steensberg; Sermed Al-Hamdani; Michael Stormly Hansen; Oliver Niels Klefter; Mette Bertelsen; Steffen Hamann

doi:10.3390/diagnostics14242797

Long-Term Visual Field Progression in X-Linked Retinitis Pigmentosa Patients

Diagnostics (Basel). 2024 Dec 12;14(24):2797. doi: 10.3390/diagnostics14242797.

Authors

Alvilda Hemmingsen Steensberg¹, Sermed Al-Hamdani¹, Michael Stormly Hansen¹, Oliver Niels Klefter^{1

2}, Mette Bertelsen³, Steffen Hamann^{1

2

4}

Affiliations

¹ Department of Ophthalmology, Copenhagen University Hospital-Rigshospitalet, 2600 Glostrup, Denmark.
² Department of Clinical Medicine, University of Copenhagen, 1172 Copenhagen, Denmark.
³ Department of Clinical Genetics, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
⁴ Neuro-Ophthalmology Department, Rothschild Foundation Hospital, 75019 Paris, France.

Abstract

We present an image that illustrates long-term visual field progression in patients with X-linked retinitis pigmentosa (XLRP) due to the retinitis pigmentosa GTPase regulator (RPGR) and retinitis pigmentosa 2 protein (RP2) gene variants. Longitudinal data from 84 genetically confirmed XLRP patients were collected from the Danish Retinitis Pigmentosa Registry, spanning the years 1948 to 2014. A visual field summation image revealed the characteristic pattern of retinal degeneration and visual field preservation in XLRP.

Keywords: Goldmann; X-linked; perimetry; retinitis pigmentosa; visual field.

Grants and funding

This research received no external funding.