Brugada syndrome is a rare condition that increases the risk of life-threatening arrhythmias. Although there are existing anesthesia recommendations for patients with Brugada syndrome, guidance on pain management is limited. We present a novel approach to pain management in these patients, illustrated by the case of a young woman with Brugada syndrome who underwent ropivacaine peripheral nerve infusion and intravenous ketamine infusion for acute-on-chronic left upper limb pain. She received perioperative multimodal analgesia, which included neuropathic agents (pregabalin, duloxetine), and opioids (morphine, codeine). Our findings contribute to a greater understanding of safe analgesic practices for patients with Brugada syndrome.
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