Mediastinal Castleman disease presenting as a paraspinal mass causing back pain and shortness of breath in a young adult

Huan Yang Chen; Shou-Hsin Wu; Fatt Yang Chew; Suat Yee Lee

doi:10.1016/j.heliyon.2024.e40792

Mediastinal Castleman disease presenting as a paraspinal mass causing back pain and shortness of breath in a young adult

Heliyon. 2024 Nov 28;10(24):e40792. doi: 10.1016/j.heliyon.2024.e40792. eCollection 2024 Dec 30.

Authors

Huan Yang Chen¹, Shou-Hsin Wu^{2

3}, Fatt Yang Chew^{2

3}, Suat Yee Lee^{4

5}

Affiliations

¹ Department of Medical Education, China Medical University Hospital, Taichung, Taiwan. No. 2, Yude Rd., North Dist., Taichung City, 404332, Taiwan, ROC.
² Department of Medical Imaging, China Medical University Hospital, Taichung, Taiwan. No. 2, Yude Rd., North Dist., Taichung City, 404332, Taiwan, ROC.
³ Department of Radiology, School of Medicine, China Medical University, Taichung, Taiwan. No. 2, Yude Rd., North Dist., Taichung City, 404332, Taiwan, ROC.
⁴ Department of Pathology, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo N Rd, South District, Taichung City, 402, Taiwan, ROC.
⁵ Department of Pathology, Chung Shan Medical University, No. 110, Section 1, Jianguo N Rd, South District, Taichung City, 402, Taiwan, ROC.

Abstract

This case report details a rare presentation of unicentric Castleman disease (UCD), hyaline vascular type in a 22-year-old woman. The patient presented with a large, well-circumscribed mass in the paravertebral region causing back pain and shortness of breath. Diagnostic imaging and biopsy confirmed the diagnosis, and surgical excision led to a favorable outcome. This case underscores the critical need to include Castleman disease in the differential diagnosis for young adults presenting with mediastinal masses. Early recognition and surgical intervention are essential for a favorable prognosis in UCD cases.

Keywords: Back pain; Case report; Dyspnea; Mediastinal Castleman disease; Paraspinal mass; Shortness of breath; Unicentric Castleman disease.

Publication types

Case Reports