Acute and chronic detrimental effects induced by short-chain chlorinated paraffins in the marine mysid Neomysis awatschensis

Seong Duk Do; Somyeong Lee; Do-Hee Lee; Minkyu Choi; Jae-Sung Rhee

doi:10.1016/j.chemosphere.2025.144069

Acute and chronic detrimental effects induced by short-chain chlorinated paraffins in the marine mysid Neomysis awatschensis

Chemosphere. 2025 Jan 3:144069. doi: 10.1016/j.chemosphere.2025.144069. Online ahead of print.

Authors

Seong Duk Do¹, Somyeong Lee¹, Do-Hee Lee¹, Minkyu Choi², Jae-Sung Rhee³

Affiliations

¹ Department of Marine Science, College of Natural Sciences, Incheon National University, Incheon 22012, Republic of Korea.
² Department of Marine Environment Research, National Institute of Fisheries Science, Busan 46083, South Korea.
³ Department of Marine Science, College of Natural Sciences, Incheon National University, Incheon 22012, Republic of Korea; Research Institute of Basic Sciences, Core Research Institute, Incheon National University, Incheon 22012, Republic of Korea; Yellow Sea Research Institute, Incheon 22012, Republic of Korea. Electronic address: jsrhee@inu.ac.kr.

PMID: 39756709
DOI: 10.1016/j.chemosphere.2025.144069

Abstract

To determine the potentially detrimental impacts of short-chain chlorinated paraffins (SCCPs), we conducted assessments of acute effects on 96-h survival rate and biochemical markers, as well as chronic and multigenerational impacts on growth and reproduction over three generations in the marine mysid, Neomysis awatschensis. Dose-dependent increase of mortality was measured in both juvenile and adult mysids for 96 h. Exposure to the LC10 value (derived from the 96-h acute toxicity value) significantly reduced feeding activity in juveniles, accompanied by a significant elevation in oxidative stress and a reduction in acetylcholinesterase activity. When juvenile and adult mysids were exposed to 1/10 of the NOEC and NOEC values for four weeks, mortality significantly increased in juveniles. Furthermore, mysids subjected to constant exposure to 1/10 of the NOEC and NOEC values across three generations, F0-F2, displayed more pronounced growth retardation, an extended intermolt duration, and a reduced rate of reproduction. These results collectively indicate that even sublethal concentrations of SCCPs can have harmful effects on the health status of mysid populations when they are consistently exposed.

Keywords: Ecotoxicity; Marine crustacean; Multigeneration; SCCPs.