Quinoline: A Novel Solution for Next-Generation Pesticides, Herbicides, and Fertilizers

Appl Biochem Biotechnol. 2025 Jan 4. doi: 10.1007/s12010-024-05164-2. Online ahead of print.

Abstract

Quinoline is a nitrogen-containing heterocycle compound widely used in the medical industry for its pharmacological properties, such as its antimalarial, antimicrobial, antiparasitic, anti-inflammatory, and anticancer activities. Beyond its medical significance, quinoline shows promising applications in agriculture as a safe and effective pesticide, herbicide, and fertilizer. This review explores the evolution of quinoline research, beginning with its history and synthesis and transitioning to its biological activities and their relevance in agriculture. It then highlights the potential applications of quinoline in modern agriculture, such as pesticides, herbicides, and fertilizers, for increasing crop yields and resilience while reducing crop waste. Moreover, it discusses formulation strategies that can enhance the efficacy of quinoline. Finally, the review addresses potential challenges, such as toxicity and environmental impact, underscoring the need for further research to harness quinoline's full potential in sustainable agriculture.

Keywords: Agricultural; Food; Growth; Quinoline; Synthesis; Yield stimulants.