Progressing nanotechnology to improve diagnosis and targeted therapy of Diabetic Retinopathy

Roghayyeh Baghban; Ehsan Namvar; Alireza Attar; Mojtaba Mortazavi

doi:10.1016/j.biopha.2024.117786

Progressing nanotechnology to improve diagnosis and targeted therapy of Diabetic Retinopathy

Biomed Pharmacother. 2025 Jan 2:183:117786. doi: 10.1016/j.biopha.2024.117786. Online ahead of print.

Authors

Roghayyeh Baghban¹, Ehsan Namvar², Alireza Attar¹, Mojtaba Mortazavi³

Affiliations

¹ Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
² Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: psorc@sums.ac.ir.
³ Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran.

PMID: 39753094
DOI: 10.1016/j.biopha.2024.117786

Abstract

The inherent limitations of traditional treatments for Diabetic Retinopathy (DR) have spurred the development of various nanotechnologies, offering a safer and more efficient approach to managing the disease. Nanomedicine platforms present promising advancements in the diagnosis and treatment of DR by enhancing imaging capabilities, enabling targeted and controlled drug delivery. These innovations ultimately lead to more effective and personalized treatments with fewer side effects. This review highlights the progress, challenges, and opportunities in developing effective diagnostics and therapeutics for DR. Additionally, it explores innovative engineering techniques that leverage our growing understanding of nano-bio interactions to create more potent nanotherapeutics for patients.

Keywords: Diabetic Retinopathy (DR); Diagnosis; Drug delivery systems; Nanomedicine; Therapy.

Publication types

Review