[Application of spiral tracheoplasty in thyroid cancer with tracheal invasion]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Dec 7;59(12):1319-1324. doi: 10.3760/cma.j.cn115330-20240408-00202.
[Article in Chinese]

Abstract

Objective: To explore the application of spiral tracheoplasty in the repair of large tracheal defects after the resection of trachea invaded by thyroid cancer. Methods: A retrospective analysis was performed on the clinical data of 11 patients, including 4 males and 7 females, aged from 36 to 67 years old, with large tracheal defects after tracheal resection due to thyroid papillary carcinoma invading the trachea in the Department of Otorhinolaryngology Head and Neck Surgery, Second Xiangya Hospital, Central South University from January 2019 to January 2022. The range of tracheal defects, time of tracheal reconstruction, postoperative complications and airway were recorded, and the patients were followed up for more than 24 months. Results: All patients underwent total thyroidectomy and tracheal resection and spiral reconstruction, and 2 of the cases underwent cricoid cartilage resection on the invaded side of cartilage. The tracheal defect accounted for 40%-60% of the circumference, and the lengths of the tracheal defects were 5.0 cm×7.5 cm and 6-9 tracheal rings, with 2 cases combined with partial defects of the cricoid cartilage. The reconstruction time was 30-60 min, with an average of 41.81 min. Among the 11 patients, 3 had recurrent laryngeal nerve paralysis, and 2 underwent tracheotomy. Four patients presented with hypocalcemia within one month after the operation. Followed up for 24-60 months, no tracheal stenosis occurred, the 2-year survival rate was 100%, the 2-year local control rate of the trachea was 100%, and the 2-year tumor-free survival rate was 81.8%. Conclusion: Spiral tracheoplasty is a safe and effective method that can reduce the tension at the tracheal anastomosis and expand the tracheal cavity, which can be used for tracheal reconstruction after extensive resection of trachea invaded by locally advanced thyroid cancer.

目的: 探索扭转气管重建在侵犯气管甲状腺癌切除后大范围气管缺损修复中的应用。 方法: 回顾性分析2019年1月至2022年1月中南大学湘雅二医院耳鼻咽喉头颈外科应用扭转气管法重建甲状腺乳头状癌累及气管切除后气管大范围缺损的11例患者临床资料,其中男性4例,女性7例,年龄36~67岁。记录气管缺损范围、气管重建时间、术后并发症及气管通畅度等评估修复效果,以及术后随访情况。 结果: 所有患者均行甲状腺全切及受累气管切除一期重建。11例患者的气管缺损占环周40%~60%,气管缺损长度为5.0~7.5 cm,缺损6~9个气管环,其中2例病变累及环状软骨者行患侧缘切除后合并部分环状软骨缺损。手术重建时间为30~60 min,平均41.81 min。11例患者中3例出现喉返神经麻痹,1例术中行气管切开,1例拔管后行气管切开。4例患者术后1个月内出现低钙。随访24~60个月,均无气管狭窄发生。患者2年生存率100%,2年气管局部控制率100%,2年无瘤生存率81.8%。 结论: 扭转气管成形术是一种安全有效的方法,可用于局部晚期甲状腺癌侵犯气管广泛切除后的缺损重建。.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Cricoid Cartilage / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Plastic Surgery Procedures* / methods
  • Postoperative Complications
  • Retrospective Studies
  • Thyroid Cancer, Papillary / pathology
  • Thyroid Cancer, Papillary / surgery
  • Thyroid Neoplasms* / pathology
  • Thyroid Neoplasms* / surgery
  • Thyroidectomy / methods
  • Trachea* / surgery
  • Tracheal Neoplasms / surgery