Daily activities change is linked to acute angle closure occurrence in COVID-19 co-infected patients

Xiaojie Wang; Aijun Tian; Shaodan Zhang; Bo Qu; Lijun Zhao; Xiaojing Pan; Peng Lu; Xinqi Chang; Lu Yang; Shaoping Ha; Jibing Wang; Jiangang Yang; Xiaohui Wang; Peng Yao; Yuxia Yang; Wenzong Zhou; Zhaoyi Wang; Juntao Zhang; Chuanqi Lin; Junhua Li; Yanhua Jiang; Zhongxia Cheng; Zhixiang Ding; Siying Xiong; Cong Ye; Houyu Zhao; Nathan Congdon; Yuanbo Liang

doi:10.1186/s12886-024-03769-z

Daily activities change is linked to acute angle closure occurrence in COVID-19 co-infected patients

BMC Ophthalmol. 2024 Dec 24;24(1):546. doi: 10.1186/s12886-024-03769-z.

Authors

Xiaojie Wang¹, Aijun Tian², Shaodan Zhang¹, Bo Qu³, Lijun Zhao⁴, Xiaojing Pan⁵, Peng Lu⁶, Xinqi Chang⁷, Lu Yang⁸, Shaoping Ha⁹, Jibing Wang¹⁰, Jiangang Yang¹¹, Xiaohui Wang¹², Peng Yao¹³, Yuxia Yang¹⁴, Wenzong Zhou¹⁵, Zhaoyi Wang¹⁶, Juntao Zhang¹⁷, Chuanqi Lin¹⁸, Junhua Li¹, Yanhua Jiang¹⁹, Zhongxia Cheng²⁰, Zhixiang Ding²¹, Siying Xiong²², Cong Ye¹, Houyu Zhao²³, Nathan Congdon²⁴, Yuanbo Liang²⁵

Affiliations

¹ National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 3250027, China.
² Hebei Eye Hospital, Xingtai City, 054001, China.
³ Department of Ophthalmology, Key Lens Research Laboratory of Liaoning Province, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, ShenYang, 10005, China.
⁴ The Third People's Hospital of Dalian, Dalian Municipal Eye Hospital, Dalian, 116011, China.
⁵ State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Qingdao Eye Hospital of Shandong First Medical University, Eye Institute of Shandong First Medical University, Qingdao, 266071, China.
⁶ Lanzhou University Second Hospital, Lanzhou, 730030, China.
⁷ Anyang Eye Hospital, Anyang, 455000, China.
⁸ Affiliated Eye Hospital of Nanchang University, Nanchang University, Nanchang, 330006, China.
⁹ Eye Hospital, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, 750001, China.
¹⁰ State Key Clinical Specialty, Weifang Eye Hospital, Zheng Da Guangming Eye Group, Weifang, 261041, China.
¹¹ Eye Hospital, The First Affiliated Hospital of Northwest University, Xi'an No.1 Hospital, Xi'an, 710002, China.
¹² The First Affiliated Hospital of Fujian Medical University, Fuzhou, 351199, China.
¹³ Ideal Eye Hospital of Soochow University, Suzhou, 215021, China.
¹⁴ Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, 518055, China.
¹⁵ Cangzhou Aier Eye hospital, Cangzhou, 061011, China.
¹⁶ Eye Hospital, China Academy of Chinese Medical Sciences, Beijing, 100040, China.
¹⁷ Department of Ophthalmology, The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China.
¹⁸ Qujing Second People' s Hospital of Yunnan Province, Qujing, 655000, China.
¹⁹ Nanxishan Hospital of Guangxi Zhuang Autonomous District, Guilin, 541002, China.
²⁰ Department of Ophthalmology, Affiliated Hospital/Clinical Medical College of Chengdu University, Chengdu, 610081, China.
²¹ Department of Ophthalmology, Guilin Medical University Affiliated Hospital, Guangxi Zhuang Autonomous Region, Guilin, 541001, China.
²² Guilin Hospital of the Second Xiangya Hospital CSU, Guilin, 541000, China.
²³ Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, China.
²⁴ Centre for Public Health, Queen's University Belfast, Belfast, UK.
²⁵ National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 3250027, China. yuanboliang@wmu.edu.cn.

PMID: 39719621
DOI: 10.1186/s12886-024-03769-z

Abstract

Objectives: To analyze the influence of daily activity-related factors associated with COVID-19 infection on the occurrence of acute angle closure (AAC).

Methods: A multicenter hospital-based study was conducted at 23 ophthalmic centers in 17 provincial-level regions across China to recruit patients with confirmed AAC during the post-lockdown time of COVID-19 (P-TOC) from Dec 7, 2022, to Jan 17, 2023, and three lockdown time of COVID-19 (TOC) periods, which included the TOC-2022 (Sep 7, 2022 - Dec 6, 2022), TOC-2021(Sep 7, 2021 - Jan 6, 2022) and TOC-2020 (Sep 7, 2020 - Jan 6, 2021). Patient information, including demographic, a questionnaire on daily activity changes during the AAC period, COVID-19 history, and eye examination results, was collected.

Results: The study involved 3216 AAC cases, with 76.2% being female and 78.9% aged over 60 years. AAC occurrences during P-TOC was nearly tripled compared to the corresponding months in TOC-2021 and TOC-2020. Patients with AAC comorbidity and COVID-19 had significantly higher water intake (37.3% vs. 2.2%, p < 0.001) and poorer sleep quality (49.16% vs. 4.07%, p < 0.001) than those without COVID-19 comorbidity, while about 58.4% of these patients received antipyretic analgesic drugs for symptom management. The COVID-19 group showed higher intraocular pressure as well as worse uncorrected distance visual acuity, when compared to non-COVID-19 patients.

Conclusions: The relationship between AAC occurrence and daily activity factors associated with COVID-19 suggests that patient management should account for changes in daily activities.

Keywords: Acute angle closure; COVID-19; Daily activity.

Publication types

Multicenter Study

MeSH terms

Activities of Daily Living*
Acute Disease
Aged
COVID-19* / complications
COVID-19* / epidemiology
China / epidemiology
Female
Glaucoma, Angle-Closure* / epidemiology
Glaucoma, Angle-Closure* / physiopathology
Humans
Intraocular Pressure / physiology
Male
Middle Aged
SARS-CoV-2
Surveys and Questionnaires

Abstract

Publication types

MeSH terms

Grants and funding