Cellular Schwannoma of the Palate Simulating as Malignant Peripheral Nerve Sheath Tumor: A Diagnostic Marathon

J Dent (Shiraz). 2024 Dec 1;25(4):383-387. doi: 10.30476/dentjods.2024.101035.2265. eCollection 2024 Dec.

Abstract

Schwannomas are considered benign soft tissue tumors that originate from Schwann cells. Oral Schwannomas are rare and account for only 1% of all Schwannomas. Cellularschwannoma (CS) is a rare histological variant of schwannoma, characterized by high cellularity and cellular atypia. We present a case of localized growth of palatal mucosa that imitated the features of malignant peripheral nerve sheath tumor (MPNST) on histopathological examination; it was differentiated from MPNST by the correlation of clinical, histopathological, and immunohistochemical features.

Keywords: Immunohistochemistry; Malignant peripheral nerve sheath tumor; Neurilemmoma; Oral neoplasms; Schwannoma.

Publication types

  • Case Reports