This report presents a patient with Legionella pneumonia (LP), initially presented with fever and mild hypoxemia, with subsequent progression to severe pneumonia during hospitalization. Despite multiple negative urinary antigen tests using Ribotest® Legionella, the diagnosis was confirmed via the loop-mediated isothermal amplification method of lower respiratory tract secretions. This case highlights the diagnostic limitations of Ribotest® Legionella and emphasizes the importance of a comprehensive diagnostic strategy, incorporating nucleic acid amplification tests or culture in suspected patients with LP. Early recognition of these diagnostic challenges is critical for optimizing patient outcomes.
Keywords: bronchoscopy; legionella pneumonia; loop-mediated isothermal amplification; ribotest® legionella; urinary antigen test.
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