1 College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China. lina@sdnu.edu.cn.
2 Laoshan Laboratory, Qingdao, 266237, P. R. China.
A nanomedicine was developed using a Cu-based metal-organic framework (MOF) to co-deliver Cu(I) and prodrugs for targeted biorthogonally catalyzed chemotherapy and chemodynamic therapy of hepatocellular carcinoma.