Invasive Candidiasis

Julia A Schroeder; Cameron M Wilson; Peter G Pappas

doi:10.1016/j.idc.2024.11.007

Invasive Candidiasis

Infect Dis Clin North Am. 2024 Dec 20:S0891-5520(24)00082-5. doi: 10.1016/j.idc.2024.11.007. Online ahead of print.

Authors

Julia A Schroeder¹, Cameron M Wilson¹, Peter G Pappas²

Affiliations

¹ University of Alabama at Birmingham, 1900 University Boulevard, 223 THT, Birmingham, AL 35294, USA.
² University of Alabama at Birmingham, 1900 University Boulevard, 223 THT, Birmingham, AL 35294, USA. Electronic address: ppappas@uabmc.edu.

PMID: 39706747
DOI: 10.1016/j.idc.2024.11.007

Abstract

Invasive candidiasis (IC) is a term that refers to a group of infectious syndromes caused by a variety of Candida species, 6 of which cause the vast majority of cases globally. Candidemia is probably the most commonly recognized syndrome associated with IC; however, Candida species can cause invasive infection of any organ, especially visceral organs, vasculature, bones and joints, eyes, and central nervous system. The optimal use of these newer diagnostics coupled with a thoughtful clinical assessment of at-risk patients and the judicious use of effective antifungal therapy is a key to achieving good antifungal stewardship and improved patient outcomes.

Keywords: Antifungals; Bloodstream infection; Candida; Fungal infection; Invasive candidiasis.

Publication types

Review