Vasoactive Intestinal Polypeptide Secreting MS Neuroblastoma

Josy Thomas; Nitin James Peters; Aravind Sekar; Deepak Bansal; Jitender Singh; Ravi P Kanojia; J K Mahajan

doi:10.4103/jiaps.jiaps_104_24

Vasoactive Intestinal Polypeptide Secreting MS Neuroblastoma

J Indian Assoc Pediatr Surg. 2024 Nov-Dec;29(6):627-629. doi: 10.4103/jiaps.jiaps_104_24. Epub 2024 Nov 5.

Authors

Josy Thomas¹, Nitin James Peters¹, Aravind Sekar², Deepak Bansal³, Jitender Singh¹, Ravi P Kanojia¹, J K Mahajan¹

Affiliations

¹ Department of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
² Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
³ Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

We present a rare case of a 17-month-old child diagnosed with MS-stage neuroblastoma and associated chronic diarrhea due to elevated vasoactive intestinal peptide (VIP) levels. The unusual occurrence of a VIP-secreting tumor in a patient with MS neuroblastoma is a rare combination, not previously reported in the literature. The patient underwent exploratory laparotomy and excision of the tumor, leading to a significant decline in VIP levels and resolution of symptoms.

Keywords: Chronic diarrhea; MS neuroblastoma; VIPoma; vasoactive intestinal peptide.

Publication types

Case Reports