Intraoperative Electrical Stapedius Reflex Testing to Monitor Cochlear Nerve Integrity during Simultaneous Vestibular Schwannoma Resection and Cochlear Implantation

Otol Neurotol. 2025 Jan 1;46(1):60-66. doi: 10.1097/MAO.0000000000004379.

Abstract

Objective: To compare the utility of intraoperative electrically evoked auditory brainstem response (eABR) and electrically evoked stapedial reflex testing (eSRT) for cochlear nerve integrity monitoring during simultaneous translabyrinthine resection of vestibular schwannoma (VS) and cochlear implantation.

Study design: Historical cohort study.

Setting: Tertiary academic referral center.

Patients: Eleven patients (12 cases) who underwent translabyrinthine tumor resection with simultaneous placement of a standard, unmodified cochlear implant (CI).

Intervention: A CI placed at the beginning of the operation before tumor resection to facilitate intraoperative cochlear nerve monitoring through a CI-delivered electrical stimulus.

Main outcome measure: Correlation of intraoperative monitoring outcomes with postoperative CI performance.

Results: Among the 12 cases (median age, 47 years), eABR waveforms were present at the conclusion of tumor resection in 10, including 6 that achieved open set speech perception. Of the 2 cases with negative eABR, 1 achieved open set speech perception. By contrast, of the 8 cases with a positive eSRT response, 7 achieved open set speech perception. Of the 4 cases with a negative eSRT response, none achieved open set speech perception. The 3 cases that did not receive auditory stimulation included 2 with positive and 1 with negative eABR; all 3 had a negative eSRT response.

Conclusions: Intraoperative eSRT using an unmodified CI is a promising new method for monitoring the integrity of the cochlear nerve during simultaneous VS resection. eSRT response at the conclusion of tumor resection strongly correlated with CI open set speech capacity. Although still useful, eABR was less reliable at predicting postoperative hearing outcomes in this series.

MeSH terms

  • Adult
  • Aged
  • Cochlear Implantation* / methods
  • Cochlear Implants
  • Cochlear Nerve* / physiopathology
  • Cohort Studies
  • Evoked Potentials, Auditory, Brain Stem* / physiology
  • Female
  • Humans
  • Intraoperative Neurophysiological Monitoring / methods
  • Male
  • Middle Aged
  • Monitoring, Intraoperative / methods
  • Neuroma, Acoustic* / surgery
  • Speech Perception / physiology
  • Stapedius / physiology
  • Treatment Outcome