6-Sulphatoxy melatonin in melancholia

Am J Psychiatry. 1985 Jan;142(1):125-7. doi: 10.1176/ajp.142.1.125.

Abstract

The daytime and nighttime levels of 6-sulphatoxy melatonin, a metabolite of melatonin, were measured in eight melancholic patients. Three patients did not show a marked nocturnal increase in 6-sulphatoxy melatonin excretion. The author discusses the relationship between melatonin and melancholia.

MeSH terms

  • Adult
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology
  • Depressive Disorder / urine*
  • Dexamethasone
  • Female
  • Humans
  • Hydrocortisone / blood
  • Male
  • Melatonin / analogs & derivatives*
  • Melatonin / metabolism
  • Melatonin / urine
  • Middle Aged
  • Psychiatric Status Rating Scales

Substances

  • Dexamethasone
  • Melatonin
  • 6-hydroxymelatonin
  • Hydrocortisone