Tinnitus and COVID-19: effect of infection, vaccination, and the pandemic

Front Public Health. 2024 Nov 26:12:1508607. doi: 10.3389/fpubh.2024.1508607. eCollection 2024.

Abstract

Introduction: The COVID-19 pandemic, which began worldwide around March 2020, has had an impact on hearing health, specifically tinnitus and hearing loss. Physiologically, COVID-19 infection, or medication used to treat the infection, has been reported to be a potential risk factor for tinnitus onset. In addition, tinnitus was reported to be a long COVID symptom or to occur after a COVID-19 vaccination in some cases. With most reports focused on the clinical population, this study aimed to investigate how the onset of tinnitus is associated with COVID-19 infection, long COVID, and COVID-19 vaccination in the general population based on self-report, while accounting for otologic and psychological symptoms.

Methods: In this study, a cross-sectional online survey that included general demographic questions, questions about tinnitus, hearing loss, hyperacusis, emotional status, and the Tinnitus Functional Index (TFI) was conducted.

Results: Completed survey data of 1,511 respondents who reported having tinnitus or believed to have COVID-associated tinnitus were included in the analysis. Participants were categorized into four groups based on their judgment regarding the etiology of their tinnitus: (1) COVID infection group, (2) long COVID group, (3) COVID vaccination group, and (4) pre-existing tinnitus group. The results suggest that tinnitus severity (estimated using TFI scores) was significantly lower in the pre-existing tinnitus group than in any of the COVID-associated tinnitus groups. While varying factors were found to contribute to tinnitus severity among the COVID-associated groups, overall, depression and/or anxiety accounted for the most variance in predicting tinnitus severity.

Discussion: The findings highlight the need to evaluate the impact of varying otologic and psychological symptoms in individuals with COVID-associated tinnitus for better patient-centered care.

Keywords: COVID infection; COVID vaccination; hearing loss; long COVID; survey; tinnitus.

MeSH terms

  • Adult
  • Aged
  • COVID-19 Vaccines / administration & dosage
  • COVID-19* / complications
  • COVID-19* / epidemiology
  • Cross-Sectional Studies
  • Female
  • Hearing Loss / epidemiology
  • Hearing Loss / etiology
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Risk Factors
  • SARS-CoV-2*
  • Self Report
  • Surveys and Questionnaires
  • Tinnitus* / epidemiology
  • Tinnitus* / etiology
  • Vaccination / statistics & numerical data

Substances

  • COVID-19 Vaccines

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work was funded by a grant from the Rainwater Charitable Foundation to FTH.