The influence of a deep learning tool on the performance of oral and maxillofacial radiologists in the detection of apical radiolucencies

Dentomaxillofac Radiol. 2025 Feb 1;54(2):118-124. doi: 10.1093/dmfr/twae054.

Abstract

Objectives: This study aimed to assess the impact of a deep learning model on oral radiologists' ability to detect periapical radiolucencies on periapical radiographs. The secondary objective was to conduct a regression analysis to evaluate the effects of years of experience, time to diagnose, and specialty.

Methods: This study used an annotated dataset and a beta version of a deep learning model (Denti.AI). The testing subset comprised 68 intraoral periapical radiographs confirmed with cone-beam computed tomography for the presence/absence of apical radiolucencies. Four oral radiologists participated in a cross-over reading scenario, analysing the radiographs under 2 conditions: initially without AI assistance and later with AI predictions. The study evaluated reader performance using Alternative Free-Response Receiver Operating Characteristic - Area Under the Curve (AFROC-AUC), sensitivity, specificity, and Receiver Operating Characteristic-Area Under the Curve (ROC-AUC) per case. It also assessed sensitivity per lesion. Regression analysis investigated how experience, time spent on images, and specialty influenced reader performance.

Results: No statistically significant differences were found in AFROC-AUC, sensitivity, specificity, and ROC-AUC. Regression analysis identified factors influencing diagnostic outcomes: unaided reading significantly prolonged diagnostic time (β = 12, 95% CI, 11-13, P < 0.001), while radiologists' professional status was positively associated with diagnostic accuracy (β = 0.02, 95% CI, 0.00-0.04, P = 0.015). These findings underscore the impact of AI on diagnostic efficiency and the critical role of radiologists' experience in diagnostic accuracy.

Conclusion: AI did not significantly enhance radiologists' overall diagnostic accuracy. However, it showed potential to enhance efficiency, particularly advantageous for non-expert clinicians. The expertise of radiologists remains vital for accuracy, underscoring the complementary role of AI in dental diagnostics.

Keywords: apical lesions; apical radiolucencies; artificial intelligence; computer vision; cone-beam computed tomography (CBCT); deep learning; dentistry; machine learning.

MeSH terms

  • Clinical Competence
  • Cone-Beam Computed Tomography* / methods
  • Deep Learning*
  • Humans
  • Periapical Diseases / diagnostic imaging
  • Radiography, Dental / methods
  • Radiologists* / statistics & numerical data
  • Sensitivity and Specificity