Concurrence of idiopathic granulomatous mastitis and breast cancer in a patient on neoadjuvant chemotherapy: A case report

Amal Mahmood; Romana Idrees; Lubna Mushtaque Vohra

doi:10.1016/j.ijscr.2024.110702

Concurrence of idiopathic granulomatous mastitis and breast cancer in a patient on neoadjuvant chemotherapy: A case report

Int J Surg Case Rep. 2024 Nov 29:126:110702. doi: 10.1016/j.ijscr.2024.110702. Online ahead of print.

Authors

Amal Mahmood¹, Romana Idrees², Lubna Mushtaque Vohra³

Affiliations

¹ Medical Student, Bachelor of Medicine and Bachelor of Surgery (MBBS), Aga Khan University, Karachi, Pakistan.
² Associate Professor, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
³ Associate Professor, Department of Breast Surgery, Aga Khan University Hospital, Karachi, Pakistan. Electronic address: lubna.vohra@aku.edu.

Abstract

Introduction: Idiopathic Granulomatous Mastitis is a rare benign inflammatory disease of the breast.

Presentation of the case: We present a case of 45-year-old woman who was diagnosed with stage II invasive ductal carcinoma in the left breast. While receiving neoadjuvant chemotherapy, she developed idiopathic granulomatous mastitis (IGM) in the left breast after the second cycle. She underwent modified radical mastectomy and has been managed with steroids for IGM on the contralateral side, which developed later in the course of the disease. This is a unique finding with limited literature available on similar cases, to the best of our knowledge.

Discussion: IGM poses a diagnostic challenge requiring histopathology for definitive diagnosis.

Conclusion: Treatment guidelines of IGM are not established making it difficult to manage.

Keywords: Case report; Granulomatous lobular mastitis; Idiopathic granulomatous mastitis; Neoadjuvant chemotherapy.

Publication types

Case Reports