The AKT1-mTOR signaling cascade is crucial for SOX3 to promote hepatocarcinogenesis

Genes Dis. 2024 May 7;12(2):101316. doi: 10.1016/j.gendis.2024.101316. eCollection 2025 Mar.

Yang Liu¹, Feifei Song¹, Xianhuang Zeng¹, Siqi Yang¹, Zixu Zhai², Ze Wang^{2

3}, Wajeeha Naz¹, Tanzeel Yousaf¹, Junwei Sun⁴, Yangjun Zhang⁵, Ying Zhou¹, Mingxiong Guo^{2

3}, Yun-Bo Shi⁶, Geng Tian⁷, Guihong Sun^{1

8}

¹ Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, Hubei 430071, China.
² Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China.
³ Ecological Research Center, College of Science, Tibet University, Lhasa, Tibet 850012, China.
⁴ Department of Hepatic & Biliary & Pancreatic Surgery, Hubei Cancer Hospital, Affiliated Hubei Cancer Hospital of Huazhong University of Science and Technology, Wuhan, Hubei 430079, China.
⁵ Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.
⁶ Section on Molecular Morphogenesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
⁷ Department of Oncology, The First Affiliated Hospital of Shenzhen University, The Second People's Hospital of Shenzhen, Shenzhen, Guangdong 518035, China.
⁸ Hubei Provincial Key Laboratory of Allergy and Immunology, Wuhan, Hubei 430071, China.

No abstract available