A visible-light-induced cascade radical trifluoromethylation/cyclization/dearomatization reaction between isocyanide-containing indoles and CF3Br has been developed to afford trifluoromethylated spiro[indole-3,3-quinoline] and spiro [indole-3,3-pyrrole] derivatives in good yields. The utility of the process is demonstrated by a scale-up experiment. The mechanism was proposed based on the control experiments. The protocol constitutes a novel and efficient route for the synthesis of trifluoromethylated 3-spiroindolenines with advantages of good generality and practical applicability, broad substrate scope, and green energy source.