Histiocyte-rich ROS1-rearranged inflammatory myofibroblastic tumour of the trachea: A rare neoplasm presenting with asthma-like symptoms

Respirol Case Rep. 2024 Dec 3;12(12):e70078. doi: 10.1002/rcr2.70078. eCollection 2024 Dec.

Abstract

Inflammatory myofibroblastic tumour is a rare tumour. We present an atypical case of Inflammatory myofibroblastic tumour which was trachea in location, histocyte rich and ROS1 rearranged. The patient presented with upper airway obstruction, which was an asthma mimic. The tumour demonstrated rapid recurrence after mechanical coring, which subsequently controlled with radiotherapy.

Keywords: ROS1 translocation; inflammatory myofibroblastic tumour.