An Unexpected Mediastinal Fibrosis Case Detected and Evaluated of Treatment Response With 18F-FDG PET/CT

Clin Nucl Med. 2025 Jan 1;50(1):e59-e61. doi: 10.1097/RLU.0000000000005568.

Abstract

IgG4-releated disease is systemic fibroinflammatory disease characterized by infiltration of IgG4-positive plasma cells in the affected tissue. Mediastinal fibrosis, which is also known as fibrosing mediastinitis, is a rare form of IgG4-releated disease. We present a case of mediastinal and retroperitoneal fibrosis in 52-year-old man who was detected with increased radiopharmaceutical uptake in 18F-FDG PET/CT imaging.

Publication types

  • Case Reports

MeSH terms

  • Fluorodeoxyglucose F18*
  • Humans
  • Male
  • Mediastinitis* / diagnostic imaging
  • Middle Aged
  • Positron Emission Tomography Computed Tomography*
  • Sclerosis / diagnostic imaging
  • Treatment Outcome

Substances

  • Fluorodeoxyglucose F18

Supplementary concepts

  • Mediastinal Fibrosis