Papillary Tumor of the Pineal Gland With Discordant FDG and FAPi Uptake

Clin Nucl Med. 2025 Jan 1;50(1):e57-e58. doi: 10.1097/RLU.0000000000005560.

Abstract

In recent years, 68Ga-FAP inhibitor has emerged as a possible substitute radiotracer to FDG for imaging of most of the tumors. Here, we report a 7-year-old girl diagnosed with recurrent papillary tumor of the pineal gland, presenting with complaints of headache and vomiting. 18F-FDG PET/CT revealed an FDG-avid enhancing lesion in the posterior part of the third ventricle. Negligible FAPI uptake was noted on the corresponding 68Ga-FAPI-46 PET/CT images, highlighting the scope of 18F-FDG PET/CT in this realm.

Publication types

  • Case Reports

MeSH terms

  • Biological Transport
  • Carcinoma, Papillary / diagnostic imaging
  • Carcinoma, Papillary / metabolism
  • Child
  • Female
  • Fluorodeoxyglucose F18*
  • Gallium Radioisotopes
  • Humans
  • Pineal Gland* / diagnostic imaging
  • Pineal Gland* / metabolism
  • Positron Emission Tomography Computed Tomography*

Substances

  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes