CREB3 protein family: the promising therapeutic targets for cardiovascular and metabolic diseases

Cell Biol Toxicol. 2024 Nov 25;40(1):103. doi: 10.1007/s10565-024-09939-5.

Abstract

Significant advancements in cardiovascular and metabolic disease research have been made with the CREB3 protein family. Studies have revealed that members of this family are crucial in the development of these diseases, contributing to the regulation of lipid metabolism, inflammation, and vascular function. These studies provide useful information for future therapeutic strategies in cardiovascular and metabolic diseases.

Keywords: CREB3; Cardiovascular and metabolic diseases; Metabolism; Transcription factor.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cardiovascular Diseases* / drug therapy
  • Cardiovascular Diseases* / metabolism
  • Cyclic AMP Response Element-Binding Protein* / metabolism
  • Humans
  • Inflammation / metabolism
  • Lipid Metabolism
  • Metabolic Diseases* / drug therapy
  • Metabolic Diseases* / metabolism
  • Molecular Targeted Therapy

Substances

  • Cyclic AMP Response Element-Binding Protein