Could the Arginine-Fluoride Association Have a Real Impact on Caries Prevention?

Abstract

In the context of preventive therapy, fluoride has allowed the reduction of the incidence and prevalence of caries. The establishment of the protective role of arginine in the neutralization of plaque acids has led to the development of new arginine-fluorine associations to potentiate this preventive aspect. Studies have reported that this association could provide superior efficacy compared to fluoride alone. A synergistic effect that could be potential and thus represent a promising ecological approach for caries prevention. However, confirmation of the effective efficacy of the arginine-fluoride association requires additional clinical studies to be carried out before establishing recommendations.

Keywords: arginine; association; biological approach; caries prevention; fluoride; toothpaste; varnish.