Complete resection of a giant epidermoid cyst of the occipital bone: case report and systematic review

CNS Oncol. 2024 Dec 31;13(1):2415279. doi: 10.1080/20450907.2024.2415279. Epub 2024 Nov 19.

Abstract

Epidermoid cysts are uncommon accounting for less than 1% of all intracranial tumors. Among them, giant intradiploic epidermoid cysts of the posterior fossa i.e. those exceeding 5 cm are an even rarer entity. Here we report on the complete resection of a 7 cm posterior fossa epidermoid cyst involving the occipital bone in a 32-year-old female presenting with an acute on chronic exacerbation of headaches and vertigo. Complete resection including the cyst wall is crucial in preventing recurrence and malignant transformation. We add to limited existing data by reporting on the first systematic review to date assessing 25 cases of giant epidermoid cysts of the posterior fossa to discuss presentation, clinical and radiographic features and definitive management strategies.

Keywords: epidermoid cysts; epidermoid tumors; giant; intradiploic; occipital bone; posterior fossa; systematic review.

Plain language summary

Epidermoid cysts are uncommon brain tumors. Under this entity, a giant cyst greater than 5 cm involving the skull bone is an even rarer entity. We describe the management of a 7 cm epidermoid cyst in a 32-year-old female presenting with acute on chronic headaches and vertigo. We add to the scant literature on this topic by providing the first systematic review to date involving the management of 25 cases of giant epidermoid cysts of the posterior fossa.

Publication types

  • Systematic Review
  • Case Reports
  • Review

MeSH terms

  • Adult
  • Epidermal Cyst* / diagnostic imaging
  • Epidermal Cyst* / pathology
  • Epidermal Cyst* / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Occipital Bone* / diagnostic imaging
  • Occipital Bone* / pathology
  • Occipital Bone* / surgery