[Of muscle and bone: Diagnostic challenge of an uncommonly located rhabdomyosarcoma]

Abstract

Rhabdomyosarcomas form a heterogeneous group of malignant soft tissue tumors characterized by immature striated muscle differentiation. Epithelioid and spindle cell rhabdomyosarcoma is a recently described entity, mainly localized intraosseously and predominantly found in young patients. Its late diagnosis and high aggressiveness confer a grim prognosis to this tumor, highlighting the importance of early recognition and appropriate management. We present herein the clinical, histopathological, immunohistochemical, and molecular aspects of this entity through a case of misleading presentation.

Keywords: Epithelioid and spindle cell rhabdomyosarcoma; Intraosseous rhabdomyosarcoma; Pathologie des tissus mous; Pathologie pédiatrique; Pediatric pathology; Rhabdomyosarcome intraosseux; Rhabdomyosarcome à cellules épithélioïdes et fusiformes; Soft tissue pathology; TFCP2.