An AIE probe for simultaneous monitoring of endogenous and exogenous hypochlorite and Zn2+ at dual channels in living cells

Abstract

Zn²⁺ and ClO^- may be associated with a variety of pathologies, and their simultaneous measurement is crucial for disease diagnosis and environmental protection. In this work, we synthesized an independent AIE probe, HNTE, through a one step reaction. The probe HNTE displayed a distinctive fluorescence color change from deep yellow to blue for ClO^- and to green for Zn²⁺. More importantly, the probe HNTE could simultaneously detect endogenous and exogenous ClO^- and Zn²⁺ in living cells colorimetrically via the blue and green channels.