Metered-Dose Inhaler Versus Nebulizer Treatment for Acute Asthma Exacerbation: A Process Evaluation

J Dr Nurs Pract. 2024 Nov 13;17(3):157-162. doi: 10.1891/JDNP-2023-0059.

Abstract

Background: The prevalence of childhood asthma in the United States is 6.5%. During the COVID-19 pandemic, a Federally Qualified Health Center (FQHC) implemented metered-dose inhalers (MDIs) with spacers instead of nebulized albuterol to reduce aerosolization of pathogens and reduce costs. Objective: The objective of the study is to assess the safety, efficacy, and efficiency of a change to the asthma exacerbation protocol at an urban FQHC. Methods: A retrospective chart review compared nebulized albuterol versus an MDI with a spacer in pediatric patients experiencing asthma exacerbation. The evaluation aimed to measure (a) the 30-day return to care in either the emergency department (ED) or clinic, (b) the total number of treatments administered, and (c) the documented use of an oral steroid with albuterol treatments. Results: Return to clinic was the only statistically significant variable. Zero MDI patients returned, whereas 61% of those nebulized returned within 30 days (p < .00001). Conclusions: Albuterol MDI with a spacer was more effective than a nebulizer in reducing follow-up visits to the clinic and was effective at reducing ED visits within 30 days. Implications for Nursing: Treating asthma exacerbations in the primary care clinic with an MDI is effective and reduces cost and airborne exposure.

Keywords: asthma exacerbation; metered-dose inhaler; nebulizer; primary health care.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Inhalation
  • Adolescent
  • Albuterol* / administration & dosage
  • Albuterol* / therapeutic use
  • Asthma* / drug therapy
  • Bronchodilator Agents / administration & dosage
  • Bronchodilator Agents / therapeutic use
  • COVID-19
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Metered Dose Inhalers*
  • Nebulizers and Vaporizers* / standards
  • Retrospective Studies
  • SARS-CoV-2
  • United States

Substances

  • Albuterol
  • Bronchodilator Agents