Challenges in metastatic hepatocellular carcinoma: beyond tumor stage in guiding treatment

Rev Esp Enferm Dig. 2024 Dec;116(12):725-727. doi: 10.17235/reed.2024.10863/2024.

Abstract

Extrahepatic metastases in hepatocellular carcinoma (HCC) often signify a poor prognosis. This case details the five-year survival of a patient with HCC and adrenal metastasis managed with an aggressive multimodal approach, including ablation, systemic therapy, and surgical resection. Despite therapeutic advances, metastatic HCC management remains a clinical challenge, underscoring the need for individualized treatment strategies beyond traditional staging systems. Further research is essential to determine the role of surgical resection and other treatment modalities in the metastatic setting.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adrenal Gland Neoplasms* / diagnostic imaging
  • Adrenal Gland Neoplasms* / pathology
  • Adrenal Gland Neoplasms* / secondary
  • Adrenal Gland Neoplasms* / therapy
  • Carcinoma, Hepatocellular* / diagnostic imaging
  • Carcinoma, Hepatocellular* / pathology
  • Carcinoma, Hepatocellular* / secondary
  • Carcinoma, Hepatocellular* / therapy
  • Combined Modality Therapy
  • Humans
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / pathology
  • Liver Neoplasms* / secondary
  • Liver Neoplasms* / therapy
  • Neoplasm Staging*