Updates in Drug-Related Pneumonitis Due to Targeted Oncologic Therapies

J Immunother Precis Oncol. 2024 Nov 1;7(4):272-282. doi: 10.36401/JIPO-24-12. eCollection 2024 Nov.

Abstract

An increasing number of newer targeted oncologic therapies approved for clinical use can cause drug-related pneumonitis. Drug-related pneumonitis can be difficult to diagnose and requires a high index of suspicion. This review serves as an update to a prior review in this journal about pneumonitis with precision oncology therapies. In this review, we focus on the incidence, timing of onset, and imaging patterns of pneumonitis associated with a number of newly approved precision oncologic agents, with a particular focus on new antibody-drug conjugate therapies.

Keywords: antibody-drug conjugate; pneumonitis; precision oncology; pulmonary adverse event.

Publication types

  • Review