Nurturing protectors: Macrophages in the human pancreatic islet

Christopher Z W Lee; Francesca M Spagnoli

doi:10.1016/j.stem.2024.10.006

Nurturing protectors: Macrophages in the human pancreatic islet

Cell Stem Cell. 2024 Nov 7;31(11):1553-1554. doi: 10.1016/j.stem.2024.10.006.

Authors

Christopher Z W Lee¹, Francesca M Spagnoli²

Affiliations

¹ Centre for Gene Therapy and Regenerative Medicine, King's College London, London, Great Maze Pond, London SE1 9RT, UK.
² Centre for Gene Therapy and Regenerative Medicine, King's College London, London, Great Maze Pond, London SE1 9RT, UK. Electronic address: francesca.spagnoli@kcl.ac.uk.

PMID: 39515296
DOI: 10.1016/j.stem.2024.10.006

Abstract

Two recent publications in Cell Stem Cell, Yang et al.¹ and Migliorini et al.,² utilized pluripotent stem cell-derived co-culture systems to explore the role of macrophages within the pancreatic islet during development and disease states.

MeSH terms

Animals
Coculture Techniques
Humans
Islets of Langerhans* / cytology
Islets of Langerhans* / metabolism
Macrophages* / cytology
Macrophages* / metabolism
Pluripotent Stem Cells / cytology
Pluripotent Stem Cells / metabolism