GABA (γ-aminobutyric acid) enrichment and detection methods in cereals: Unlocking sustainable health benefits

Abstract

Gamma-aminobutyric acid (GABA), a non-protein amino acid primarily biosynthesized in cereals, is vital to the human neurological system. As the primary neurotransmitter, it promotes relaxation, inhibits depression and sleeplessness, and regulates synaptic transmission and neuronal development. GABA also protects the liver, kidneys, and intestines, reduces blood pressure, and fights cancer and inflammation. Colorimetric and enzyme-based procedures, biosensors, and High-Performance Liquid Chromatography primarily detect GABA. GABA content is enriched by treatments, like germination and fermentation, suitable and economical methods on industrial scales. Moreover, ultrasonication, abiotic stress, heat, and relative humidity are also utilized for GABA enrichment. With advancing technology and knowledge of the nutrients concerning human health, target-specific nutrition utilizing sustainable ingredients needs exploration. Conclusively, the current article delves into the latest developments in GABA enrichment and detection techniques and GABA's potential health benefits. Further studies are required to understand and refine enrichment procedures to develop GABA-enriched foods with health-promoting qualities.

Keywords: Cereals; Enrichment: health benefits; Glutamate decarboxylase; γ-aminobutyric acid (GABA).