Hypocalcaemia owing to severe vitamin D deficiency in two children with autism spectrum disorder and food allergy

Paediatr Int Child Health. 2024 Sep-Nov;44(3-4):146-150. doi: 10.1080/20469047.2024.2422661. Epub 2024 Nov 6.

Abstract

Individuals with autism spectrum disorder (ASD) often exhibit limited food preferences and sensory sensitivity. Co-existing food allergies in this population can further limit their already restricted diets, increasing the risk of nutritional deficiencies. Two children with ASD and food allergies presented with non-specific symptoms and were found to have hypocalcaemia secondary to severe vitamin D deficiency. The report highlights the importance of a greater degree of suspicion of vitamin D deficiency in children with co-existing ASD and food allergies. Non-specific symptoms related to hypocalcaemia can be difficult to evaluate in non-verbal patients. A thorough dietary history is an essential part of the care of children with ASD. It is proposed that limited diets should be screened for common nutritional deficiencies.

Keywords: Autism spectrum disorder; children; food allergies; hypocalcaemia; vitamin D deficiency.

Publication types

  • Case Reports

MeSH terms

  • Autism Spectrum Disorder* / complications
  • Child
  • Food Hypersensitivity* / complications
  • Humans
  • Hypocalcemia* / etiology
  • Vitamin D Deficiency* / complications