Clinical outcomes of patients with heterotopic pregnancy after laparoscopic surgery

Eur J Obstet Gynecol Reprod Biol X. 2024 Sep 27:24:100342. doi: 10.1016/j.eurox.2024.100342. eCollection 2024 Dec.

Abstract

Objective: This retrospective study aims to analyze laparoscopic surgical management and clinical consequences of patients with heterotopic pregnancy (HP) who underwent in vitro fertilization and embryo transfer (IVF-ET) and laparoscopic surgical management.

Material and methods: We conducted a retrospective analysis of clinical characteristics and pregnancy results of patients with HP who underwent IVF-ET at the Affiliated Maternity and Child Health Care Hospital of Nantong University between January 2013 and December 2022.

Results: 21 patients were diagnosed with HP, with an average diagnostic period of 49.1 ± 11.1 days. 11 cases (52.4 %) exhibited clinical manifestations such as abdominal pain and vaginal hemorrhage before the surgery, while 10 cases (47.6 %) were asymptomatic prior to diagnosis. All patients underwent laparoscopic surgery, resulting in 8 cases of miscarriage postoperatively (6.15 %), and all 13 neonates showed no anomalies at birth.

Conclusion: Laparoscopic surgery is a safe and effective treatment, and most patients can achieve satisfactory pregnancy outcomes after surgery.

Keywords: Assisted reproductive technology; Heterotopic pregnancy; Laparoscopic surgical treatment; Pregnancy outcome.