Silicone on the Move: Migratory Siliconoma After Retinal Surgery Report of a Case and Review of the Literature

Am J Dermatopathol. 2024 Dec 1;46(12):e124-e127. doi: 10.1097/DAD.0000000000002769. Epub 2024 Oct 15.

Abstract

Silicone granulomas, or "siliconomas," are the common foreign-body inflammatory responses to injected silicone material. In rare cases, siliconomas develop remotely from the original site of injection, secondary to silicone migration. If a history of silicone injection is not noted, such lesions risk misdiagnosis (possibly as infection or malignancy). Intraocular silicone oil is commonly used in retinal detachment surgery, with occasional reports of granulomatous responses after its application in this context. Here, we report a 66-year-old man who developed a periocular silicone granuloma years after scleral buckle surgery for a detached retina and summarize the literature of similar reports of migratory siliconoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Foreign-Body Migration / etiology
  • Granuloma, Foreign-Body* / diagnosis
  • Granuloma, Foreign-Body* / etiology
  • Granuloma, Foreign-Body* / pathology
  • Humans
  • Male
  • Retinal Detachment* / etiology
  • Retinal Detachment* / surgery
  • Scleral Buckling* / adverse effects
  • Silicone Oils / adverse effects
  • Silicones* / adverse effects

Substances

  • Silicones
  • Silicone Oils