Limited stage high grade B-cell lymphoma with MYC, BCL2 and/or BCL6 rearrangements: BCL2 rearrangements drives the poor outcomes

Blood Cancer J. 2024 Oct 14;14(1):178. doi: 10.1038/s41408-024-01148-x.

Authors

Jennifer K Lue¹, Efrat Luttwak², Alfredo Rivas-Delgado², Helen Irawan³, Alexander Boardman², Philip C Caron², Kevin David², Zachary Epstein-Peterson², Lorenzo Falchi², Paola Ghione², Paul Hamlin², Steven M Horwitz², Andrew M Intlekofer², William Johnson², Anita Kumar², Alison Moskowitz², Ariela Noy², M Lia Palomba², Ralphael Steiner², Robert Stuver², Pallawi Torka², Santosha Vardhana², Andrew D Zelenetz², Heiko Schoder⁴, Brandon Imber⁵, Joachim Yahalom⁵, Yanming Zhang³, Pallavi Galera³, Ahmet Dogan³, Umut Aypar³, Gilles Salles²

Affiliations

¹ Lymphoma Service, Division of Hematological Malignancies, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. luej@mskcc.org.
² Lymphoma Service, Division of Hematological Malignancies, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
³ Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
⁴ Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
⁵ Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Adult
Aged
Aged, 80 and over
Female
Gene Rearrangement*
Humans
Lymphoma, B-Cell* / genetics
Lymphoma, B-Cell* / pathology
Male
Middle Aged
Neoplasm Grading
Prognosis
Proto-Oncogene Proteins c-bcl-2* / genetics
Proto-Oncogene Proteins c-bcl-6* / genetics
Proto-Oncogene Proteins c-myc* / genetics

Substances

Proto-Oncogene Proteins c-bcl-6
Proto-Oncogene Proteins c-bcl-2
BCL6 protein, human
Proto-Oncogene Proteins c-myc
BCL2 protein, human
MYC protein, human

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