Background: In recent years, depression has increasingly become a major global public health issue. Among its common physical symptoms, sleep disturbances are prevalent in individuals with depression and are considered a risk factor for the progression of the disorder. Poor sleep quality may be a significant contributor to depression among college students. However, the EEG indicators that are commonly associated with depressive symptoms and sleep quality, as well as the effects of physical exercise on these EEG indicators, remain unclear.
Purpose: This study aims to explore the relationship between physical activity levels, depressive symptoms, and sleep quality among college students, based on resting-state electroencephalography (EEG) data in a cross-sectional study.
Methods: A total of 342 college students were recruited to assess physical activity levels, depressive symptoms, sleep quality, and EEG data. Pearson correlation coefficients were used to evaluate the relationships among these variables, and the PROCESS macro (Model 4) for SPSS was applied to examine the mediating role of sleep quality in the relationship between physical activity levels and depressive symptoms, with mediation effects tested using the bootstrap method.
Results: A significant difference was observed in the Pittsburgh Sleep Quality Index (PSQI) total scores between students with and without depressive symptoms (T = 9.746, P < 0.001). Students with depressive symptoms showed poorer sleep quality across various dimensions, including sleep duration, sleep onset latency, sleep disturbances, and daytime dysfunction. Depression symptom were positively correlated with Sleep Quality (r = 0.547, P < 0.001), indicating that higher depression symptoms are associated with poorer sleep quality. Correlations between depressive symptoms and EEG power values revealed significant associations with theta and beta2 frequencies in multiple brain regions (P < 0.05). Physical exercise showed a significant negative correlation with Sleep Quality scores (r = -0.158, P = 0.004), and with sleep duration (r = -0.141, P = 0.011) and daytime dysfunction (r = -0.142, P = 0.010). Additionally, physical exercise was negatively correlated with theta band power at F8 (P < 0.05). Mediation analysis demonstrated that physical exercise has a direct effect on depressive symptoms (β = -0.123, 95 % CI = -0.287 to -0.069) and an indirect effect through improved sleep quality (β = -0.074, 95 % CI = -0.089 to -0.016), accounting for 60.16 % and 40.65 % of the total effect, respectively.
Conclusion: These findings provide a theoretical basis for developing precise exercise intervention programs to improve depressive symptoms and sleep quality among college students. The results indicate that moderate physical activity can help alleviate depressive symptoms and improve sleep quality, thereby enhancing the overall health of college students.
Keywords: College students; Depressive symptoms; EEG; Physical exercise; Sleep quality.
Copyright © 2024. Published by Elsevier B.V.