Drug abuse and ACS in the very young (less than 30 years): Demographic, clinical and angiographic profile

Indian Heart J. 2024 Sep-Oct;76(5):355-357. doi: 10.1016/j.ihj.2024.10.003. Epub 2024 Oct 10.

Abstract

Aim: To identify incidence, type of drug abuse study clinical and angiographic profile in very young population presenting with acute coronary syndrome (ACS).

Materials and methods: All consecutive patients less than 30 years with ACS included and segregated into Group 1 and 2 (with and without drug abuse respectively) RESULT: n = 153; n = 17 in group 1 of whom 35.29 % consumed opium, 17.64 % energy drinks, 17.64 % whey protein supplements, 17.64 % inhaled marijuana, 5.88 % heroin and spasmoproxyvon and 23.52 % multi-substance abusers. STEMI, Single vessel disease and urban domicile were predominant. Rising trends of drug abuse were identified in prospective (28.20 %) versus retrospective (5.30 %) timeframe (p = 0.011).

Conclusion: Rising trends of drug abuse, a potentially modifiable risk factor of ACS in the young are alarming. Strict regulations are needed to curb this menace.

Keywords: Acute coronary syndrome; Drug abuse; Young.

MeSH terms

  • Acute Coronary Syndrome* / diagnosis
  • Acute Coronary Syndrome* / epidemiology
  • Adult
  • Coronary Angiography*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • India / epidemiology
  • Male
  • Prospective Studies
  • Retrospective Studies
  • Risk Factors
  • Substance-Related Disorders* / epidemiology
  • Young Adult