Indian Experience with Vericiguat: A Review Based upon Case Series

J Assoc Physicians India. 2024 Oct;72(10):63-68. doi: 10.59556/japi.72.0696.

Abstract

Heart failure (HF) is a condition that can result in repeated hospitalizations every year and can result in worsening HF (WHF). Although current pharmacological treatment for HF is fairly effective, there is a need to lower the residual risk of cardiovascular events and hospitalizations. Vericiguat, a soluble guanylate cyclase (sGC) stimulator, a new entrant, seems to present a promising therapeutic option for HF with signs of worsening, and early initiation of this therapy may be beneficial in certain patient profiles. This article explores the potential benefits of early vericiguat initiation in four patient profiles who presented with WHF.

Publication types

  • Review

MeSH terms

  • Aged
  • Benzoates / therapeutic use
  • Female
  • Heart Failure* / drug therapy
  • Humans
  • India
  • Male
  • Middle Aged
  • Pyrimidines

Substances

  • Benzoates
  • Pyrimidines
  • vericiguat