[Reirradiation of recurrent breast carcinoma]

Abstract

Approximately 10 to 15% of patients with breast cancer will have a local recurrence after initial conservative treatment or mastectomy. Total mastectomy has historically been the standard treatment for local recurrence. However, the question of reirradiation may arise as part of a second conservative treatment in conjunction with segmentectomy or in the case of chest wall recurrence to improve local control. Different modalities are available: brachytherapy, external beam radiotherapy with or without hyperthermia. Although the carcinologic results are encouraging, this complex situation requires rigorous patient selection and technical requirements to achieve the best local control and limit toxicity events. This article presents a review of the literature on the different indications and techniques for reirradiation of ipsilateral recurrent breast cancer, with the aim of providing decision support in clinical practice.

Keywords: Brachytherapy; Breast cancer; Cancer du sein; Curiethérapie; Efficacité; Efficacy; Radiation therapy; Radiothérapie; Recurrence; Reirradiation; Récidive; Réirradiation; Toxicity; Toxicité.